Stem cells predominantly are known as ‘master cells’ of human body, due to their capability to develop other systems, organs and tissues in the body. Stem cells can be regarded as the immune system and blood’s building blocks. They are rather the blood system’s factory and can make new copies continuously of themselves, thus producing cells to create every blood type like platelets, white blood cells and red blood cells. Basically, there are three sources present where there can be found stem cells.
- Umbilical cord blood
- Peripheral blood
- Bone marrow
Different researches conducted in this field have suggested that the obtained stem cells from the cord blood are found to be much more beneficial when compared to those which have been retrieved from peripheral blood or bone marrow. This is because, they appear versatile and also are younger. They also tend to demonstrate crucial characteristics with the embryonic stem cells, while differentiating into almost all cell types within the body.
The second aspect is that cord blood stem cells can be availed easily, since they are found during delivery time from the placenta. Hence, trying to harvest stem cell especially from the bone marrow does required surgical procedure performed using general anesthesia. It causes small risk or post operative pain in the donor. The best allogenic bone marrow transplant hospitals in India will ensure that both the patient receiving BMT and the donor is safe and in good health after the procedure.
Stem cells when used for medical treatments is said to be the focus among researchers performing different types of projects, the results of which are found to be encouraging.
- Diseases like Parkinson’s and Alzheimer’s get treated using stem cells found in cord blood.
- Even they can efficiently treat heart diseases, thus allowing the patients to develop their own bypass.
- The stem cells also have the potentiality to cure several life threatening ailments such as non-Hodgkin’s lymphoma, leukemia, inherited disorders, anemia including other deficiencies related to the immune system.
- Life style diseases like heart ailments, liver disorders and diabetes could be treated using stem cells.
Cord blood related stem cells are said to have benefitted recipients in huge numbers. They can be stored and then transplanted again into the donor, to the unrelated recipient or any family member. To ensure successful bone marrow transplantation, it is necessary to have perfectly matching tissue proteins among the recipient and the donor. Upon using stem cells from the cord blood, door cells tend to appear to engraft or take, even if partial tissue mismatches.
There are few complications such as GVHD (graft vs. host disease), where donor cells could attack tissues of the recipient. This is likely to occur less in cord blood when compared to bone marrow. The reason is because, muted immune system is present in cord blood and certain cells are generally active in immune reaction. According to researches conducted, children receiving cord blood transplantation from the closely matched sibling will develop 59% less GVHD when compared to those recipients having received BMT from closely matched sibling.
The well known allogenic bone marrow transplant hospital in India will offer its patients with immense respite and satisfaction.